Dermatology Practical & Conceptual

Primitive non-neural granular-cell tumor (PNGCT) is a rare tumor of uncertain lineage. It was first described by Le Boit et al. [1] as “primitive polypoid granular cell tumor” after analysis of four cases. Since then various other names have been proposed. Lazar et al. called it “primitive non-neural granular cell tumor” [2] and Chaudhry et al. coined the term “dermal non-neural granular cell tumor” [3]. Unlike conventional granular cell tumor, PNGCT is not of neural or Schwannian lineage, and the precise line of differentiation is still unclear [2,3]. Herein we describe a case of this rare and intriguing entity in which the clinical and dermoscopic pattern guided the management for excision although only histological and immunohistochemical evaluation allowed to make the correct diagnosis. Case report